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The Pain Paradox
Health & Mind

The Pain Paradox

Why Chronic Pain Is So Hard to Treat — and What New Science Is Revealing About Its Origins

Elena Vasquez

Pain medicine specialist and neuroscientist at the University of California, San Francisco, studying the mechanisms of chronic pain and developing new treatment approaches.

January 20, 2026·8 min read

The Pain Paradox

Chronic pain affects more than 50 million Americans and costs the economy more than $600 billion per year. Despite decades of research, it remains poorly understood and inadequately treated. New insights into the neuroscience of pain are challenging the traditional model and opening new avenues for treatment.

TOPICS
chronic painneurosciencemedicineopioid crisistreatment
FURTHER READING
NIH: Pain Research
NIH
International Association for the Study of Pain
IASP
Nature Reviews Neuroscience: Pain
Nature Reviews
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